Alzheimer’s or Alzheimer’s disease is a neurodegenerative disease, that most people have heard about. It is the 6th leading cause of death in the United States according to the Alzheimer’s Association, and it kills more people than breast cancer and prostate cancer combined. But although there is no ‘big pharma’ medication that decreases the risk of getting Alzheimer’s and up to now there is no cure, recent scientific research has shown very promising effects of CBD for Alzheimer’s.
Every 66 seconds in the US someone develops the disease according to the Alzheimer’s Association.
Alzheimer’s causes 60% to 70% of dementia cases and is an unpleasant disease for the patient but also for its loved ones and caregivers.
The Alzheimer’s Association states that one in three seniors dies from Alzheimer’s or other dementia.
Cannabis for preventing and reversing Alzheimer’s
Preliminary research indicates that several of the effects cannabidiol (CBD) has on Alzheimer’s could be therapeutically beneficial. A major part of the neurodegeneration in the disease and Alzheimer’s progression are linked to the neuroinflammatory response and reactive gliosis. Cannabidiol has proven in studies to be able to reduce these two processes.
Besides that, other studies have shown that CBD stimulates neurogenesis, which is the development and growth of neurons. This causes the deterioration process of the cognitive functions to slow down. Preclinical animal tests have even demonstrated that cannabidiol can prevent or reverse the cognitive deficit development.
Like with several other medical conditions, like for example cannabis cancer treatment, also in Alzheimer’s better health effects of CBD are achieved when combining CBD with THC, studies have shown. THC is the psychotropic component of hemp and cannabis, but when the correct ratio and dosing are followed the synergetic effect of these two cannabinoids significantly improves the above-mentioned effects.
A 2016 study, “Cannabidiol Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells” found that cannabidiol (CBD) led to the downregulation of Alzheimer’s linked genes. Furthermore, the study found that CBD neutralized one of the main players in Alzheimer’s disease, pathogenesis.
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Gary Wenk, professor of neuroscience, immunology and medical genetics at Ohio State University, spent much of his career looking for a drug that could reduce brain inflammation and restore cognitive functioning. His lab tests concluded that cannabinoids were effective in doing so.
“I’ve been trying to find a drug that will reduce brain inflammation and restore cognitive function in rats for over 25 years; cannabinoids are the first and only class of drugs that have ever been effective. I think that the perception about this drug is changing and in the future people will be less fearful.” , according to professor Gary Wenk.
A 2010 PubMed publication studies “Cannabinoids and Dementia: A Review of Clinical and Preclinical Data”, with Alzheimer’s as one of the four neurodegenerative diseases reviewed. The study reveals that two clinical trials have been carried out on Alzheimer’s and one case report on it is available.
All reports concluded to have seen significant behavioral improvement in late-stage Alzheimer’s patients and mostly no side effects were reported.
Accoding to Dr. Gary Wenk, those baby boomers who smoked a lot of marijuana during the flower power period, suffer by far less from Alzheimer’s today.
CBD Oil Dosage for Alzheimer’s
As can be seen in the different studies, better results are achieved when using both CBD and THC, with THC in much lower quantities to avoid getting high. Therefore we recommend taking a full spectrum hemp oil like from Cannabidiol Life of which cannabidiol is the main component but which also contains other cannabinoids like THC in small (and legal) quantities.
Besides the fact that we are all a little different and therefore will react slightly different to CBD, the severity of the Alzheimer’s disease is the main indicator of the quantity. Although it is not possible to overdose cannabidiol, it is unnecessary to take too much if it is not needed.
We, therefore, recommend starting with a smaller dose, like 40 or 50 mg per day and double it after 4 days if it doesn’t improve or if the improvements are too frail. Alzheimer’s patients have been known to have taken up to 400 mg daily in the beginning to reverse the disease.
No matter how you take the CBD oil, it is recommended to stay at the higher dosage for several weeks and when the patient has returned to its normal functioning to go back to a maintenance dosage of anywhere in the range of 25 to 50 mg per day. Just find out by trial and error what the minimum dosage is for avoiding a return of memory loss, agitation etc.