He has both original articles and review articles published in peer-reviewed international journals.
Diabetes is a disease where your blood sugar, also called glucose, is too high. Although according to scientific and anecdotal reports CBD for diabetes is more effective and safer, than pharmaceutical medicines, it is still rather unknown.
More than 100 million people in the United States have diabetes or are prediabetic, according to the CDC (Center of Disease Control and Prevention). According to the same report, 30.3 million Americans—nearly 1 in 10—have diabetes.
The World Health Organization predicts that by 2030 the number of people with diabetes will double. If we take a look at the history of diabetes in the last decade, the number of people diagnosed with diabetes jumped by almost 50 percent. This indicates that diabetes is not some kind of ”abstract, mysterious” illness.
According to the CDC nearly 16% of adults diagnosed with diabetes were smokers, nearly 90% were overweight and more than 40% were physically inactive.
Diabetes is likely caused by society’s external impacts. Since we know that it’s a metabolic disease, by default we conclude that the highest risk of being diagnosed as diabetic is due to one’s individual lifestyle and nutrition.
From 2011 to 2015, diabetes in canines increased by 32%. Luckily cannabidiol dog oil works just as well for humans as it does for dogs and a significant improvement of the diabetes condition can be achieved.
CBD Impact on Diabetes
Even though the public is more scared of AIDS, we have more people dying from Diabetes than HIV. It’s no wonder, when even an average medically-informed person knows that diabetes causes kidney failure, blindness, amputations, heart failure and stroke.
Before we jump into the scientific, clinical, and anecdotal studies, let’s start with one of CBD’s effects and CBD oil benefits. Besides commonly known effects like pain relief with CBD, CBD is known as the natural remedy for diabetes.
“Unlike insulin, CBD diabetes treatment may actually suppress and perhaps cure the disease,” – Mark J. Rosenfeld, CEO of ISA Scientific.
One of the best and most trusted studies is a result of many years of research and testing done by scientists Raphael Mechoulam and Ruth Gallily from the Hebrew University. This research clarified that CBD can treat the inflammation caused by a sugar-imbalance in the blood.
At first, scientists focused on the discovery of how insulin unlocks cells and lets glucose enter so that it can activate the energy that our body needs. Then, they distinguished between Type 1 and Type 2 Diabetes. In addition, experiments on rats treated with CBD show the involvement of the endocannabinoid system.
Cannabinoid receptors have been identified in the pancreas, which automatically means it plays a role in decreasing the severity of diabetes. This is the process in which cannabinoid receptors play an essential role in the pancreas the insulin producer that our body depends on for energy.
Another important and strong piece of evidence from the experiment on rats is that CBD has a positive impact on decreasing inflammation of pancreatic cells. Results from a study conducted on rats with infarcts (areas of dead tissue) due to a blood supply failure showed that after CBD treatment, the infarcts were reduced by 30%.
Diabetes Type 1 and Diabetes Type 2
A study conducted in Israel in 2015, led by Raphael Mechoulam, indicated that the anti-inflammatory properties of cannabidiol could treat both diabetes type 1 and 2. A year later, in 2016, the improved research showed that an experimental CBD treatment reduced inflammation in the microcirculation of the pancreas in mice.
An autoimmune disease study, published in ‘Autoimmunity Journal’, drafts that injections of 5 mg per day of CBD significantly reduced the level of diabetes in mice.
The same team went even further and reported that 60% of the mice treated with CBD remained diabetes-free for 26 weeks, in comparison to those without CBD treatment.
How did CBD succeed in decreasing inflammation in mice? Quite simply, it’s the anti-inflammatory properties of cannabidiol. Another study on rodents at the Medical College of Georgia discovered that the CBD cannabinoid protected eyes from retinal cell death and breakdown of the blood-retinal barrier.
Lead scientist, Dr. Liou explained, “What we believe cannabidiol, as an antioxidant, does is to neutralize the toxic superoxides. Furthermore, it inhibits the self-destructive system and allows the self-produced endogenous cannabinoids to stay there longer by inhibiting the enzyme that destroys them.”
First of all, clinical trials confirmed that both CBD and THC are ”safe profile” compounds which can effectively treat a metabolic disorder such as diabetes.
Clinical trials also confirmed that CBD plays a major role in decreasing and treating both diabetes type 1 and type 2.
When it comes to diabetes type 1, one of the studies in the US also confirmed this. Patients who were treated with cannabis had 16% lower fasting insulin levels, and 17% of insulin resistance. The examined non-users didn’t experience the same progress. The rest of the studies in this category also endorsed the fact that CBD is a stronger antioxidant than vitamin E or C.
A UK research team launched a clinical pilot trial to examine the CBD effect in type 2 diabetes patients.
The method they used was a placebo-controlled and double-blinded format. The examined group received a dosage of 100 mg twice daily for the duration of 13 weeks. The targets were patients with type 2 diabetes.
The results were great; a change in HDL-cholesterol concentration, insulin sensitivity, body weight, glycemic control, lipid profile and very important markers of inflammation were observed.
A British company GW Pharmaceuticals also included CBD in a type 2 diabetes trial. The results showed an improved insulin response and greater pancreatic cell function as well as significantly reduced blood pressure levels.
A study under the name “Marijuana in the Management of Diabetes” confirmed that cannabis users are less likely to become obese. Additionally, another finding is that cannabis or CBD users develop “good cholesterol” and have better carbohydrate metabolism than non-users.
Clinical Trials in the Pipeline
Based in Israel, ISA Scientific has launched a global collaboration and licensing agreement in order to advance CBD therapies. In a statement, ISA Scientific CEO Mark J. Rosenfeld said, “The licensing agreement is very well timed because our Phase 1 clinical trials on dosing and safety are now underway in Israel and arrangements for Phase 2 trials for treating diabetes are in process.”
CBD hemp oil is a life-savior and this has been and is still being confirmed by strong anecdotal evidence. The result that, patients find to be the most impressive is that CBD is the key factor for establishing homeostasis, in other words; stable internal functioning despite fluctuations in the external environment.
One of the patient stories is about C.W., a 36 years old man in California diagnosed with type 1 diabetes. He is living proof that Cannabis and CBD helped him with the complications such as “Diabetic Retinopathy”. With the advice of a doctor and with an official recommendation for using marijuana, this patient took control of his blood sugar and other diabetic complications.
The treatment confirmed CBD’s effect of reducing oxidative stress on the nervous and circulatory systems. Time Magazine reports the endorsement by the Harvard Med School researcher Murray Mittleman that current diabetic patients on CBD treatment witness a gradually normalized blood-sugar level.
CBD Oil Dosage for Diabetes
On this site, we always indicate the dosage amount in milligrams CBD. The number of drops varies per product because of different concentration levels. If you take the number of milligrams as your dosage unity, the concentration basically does not matter. For the same milligram dosage, the number of drops may vary depending on brand and type.
With very high dosage levels and low concentration oils, you will have to take many drops. Therefore, often in these situations, people use higher concentration oils. Besides that, almost always, the higher concentration oils are more priceworthy.
The first thing that a patient should consider when it comes to dosage for CBD diabetes treatment is the severity of the condition. People with mild issues require less dosage than those with more severe conditions.
CBD Dosage for Mild Diabetes Symptoms
For Mild diabetes conditions, people usually take 40 to 50 milligrams CBD daily and monitor their blood-sugar level. Based on that they either increase or, decrease with 10-20 mg steps or, if they are satisfied with the results, maintain the same dosage level.
CBD Dosage for Severe Diabetes Symptoms
For severe diabetes conditions, people usually start with 100 or 150 milligrams CBD daily and monitor their blood-sugar level, just like described above. Based on your blood-sugar level you should be able to start decreasing the insulin amounts. Often, diabetes patients can completely eliminate insulin intake after gradually having decreased their insulin.
As a maintenance dosage, to maintain your health-balance or homeostasis, a dosage of 20 to 25 mg is common. Because it is impossible to overdose CBD, you can safely experiment with the dosage level, monitoring the effects and your blood-sugar level.
General dosage guidelines are as follows:
- Start small.
- Increase if the improvement dynamics are too weak until you see good improvement dynamics.
- Decrease when you see strong improvement dynamics and monitor to keep the same dynamics with less dosage.
- Keep the same dosage level if you see good improvement dynamics and decreasing results in weakening of the dynamics.
A single CBD dose of 20-40 mg under the tongue. Doses greater than 40 mg may actually increase eye pressure.
There are many methods of CBD use. The most common way is in the form of oil or tincture where CBD should be first held under the tongue, to be absorbed in the mouth for at least one minute, before swallowing. This method of intake is called the sublingual intake.
With sublingual intake, some of the CBD taken will be broken down by the digestive system, but most of it will be absorbed by your body directly, shortening the effect lead time. Other oral methods include capsules, mouth strips, and edibles such as chocolate bars.
Many people also enjoy using CBD oil via vaporizers or inhalers as this is a near instant delivery method that can be quite effective, but not as long lasting as sublingual and oral intake. Others use CBD oil by topical skin absorption via lotions, balms, creams or patches.
The amount of CBD can be indicated in different ways on the packaging of different brands. Often, they indicate the number of milligrams of CBD and the total amount of drops in the bottle. This makes it easy for you to calculate how many drops you need to take your daily dosage. If not, just use our CBD calculator.
Success Stories of Diabetes Patients
We have carefully collected CBD testimonials for this particular condition to serve as proof and inspiration to others. Do not hesitate to record your own experience and share it with us so we can add it to this list and help thousands more patients.
Overview of Scientific Studies and Reports
If you are interested in the medical proof and not scared of reading through some professional medical jargon, check out the studies below.
Scientific Reseach Studies on Diabetes
- 2006/01 – Neuroprotective and blood-retinal barrier-preserving effects of CBD in experimental diabetes
- 2006/03 – CBD lowers incidence of diabetes in non-obese diabetic mice
- 2008/01 – Cannabidiol arrests onset of autoimmune diabetes in NOD mice
- 2008/08 – The endocannabinoid system in obesity and type 2 diabetes
- 2010/03 – Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
- 2010/03 – Cannabinoid modulation in a model of murine type I diabetic peripheral neuropathic pain
- 2010/12 – CBD attenuates cardiac dysfunction, oxidative stress, fibrosis, inflammatory and cell death in diabetes
- 2011/00 – Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
- 2012/02 – The endocannabinoid system and plant-derived cannabinoids in diabetes and diabetic complications
- 2013/07 – The impact of marijuana use on glucose, insulin, and insulin resistance among US adults
- 2013/11 – Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes
- 2014/01 – Biochemical and immunohistochemical changes in delta-9-tetrahydrocannabinol-treated type 2 diabetic rats
- 2016/00 – Experimental cannabidiol treatment reduces early pancreatic inflammation in type 1 diabetes
- 2016/10 – Efficacy and Safety of CBD and THC-V on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes