People have been using CBD for inflammation for a long time. But especially relevant is that its efficacy in this field is scientifically proven. First of all, inflammation is an indication that the body is fighting harm and that it is healing itself. It is, therefore, a good thing, as long as it doesn’t get chronic.
“The Secret Killer: The Role of inflammation in Heart Disease, Cancer, Alzheimer’s and other Chronic Diseases”. This 2004 Time Magazine cover story portays inflammation as the engine driving heart disease, cancer, Alzheimer’s, but also obesity and diabetes.
So, add up the number of people suffering from heart disease, cancer, Alzheimer’s, and diabetes. Then finnaly ignore the fact that people might have multiple conditions at the same time. And the result is: 50 million Americans (15%) suffer from a condition with chronic inflammation at the basis of it.
15% of the population deals with inflammation
Most noteworthy is that these numbers will dramatically rise during the next years. The responsible governmental foundations predict dramatic increases of, especially diabetes, cancer and Alzheimer’s. Ironically the cure for many of these conditions is the natural plant that has been around longer than humankind: Cannabis.
How to treat cancer with CBD and cannabis and what CBD dosage for Alzheimer’s is the best? Read it in the relevant articles. Scientific research proved that CBD and/or cannabis are extremely effective with most inflammatory conditions. The only problem is, that ‘Big Pharma’ is against cannabis, for understandable, but not humanitarian reasons.
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Cannabidiol for Curing Acute and Chronic Inflammation
A group of scientists studied already in 2007 the effects of cannabis on multiple sclerosis. Especially relevant though is that at that time, the FDA had recently approved cannabidiol for the treatment of inflammation, pain, and spasticity associated with multiple sclerosis.
Of course, they tested with synthetic cannabinoids, coming from the ‘big pharma’ factories. But natural CBD from the plant is a lot more effective than synthetic CBD. Furthermore, it doesn’t have the nasty side-effects that come with pharmaceutical drugs (including synthetic cannabinoids).
Researchers carried out a lab study on a rat model of acute inflammation in 2004. As a result, they concluded that the Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of CBD. Yet another lab study in 2007 stated that CBD has proven potent anti-inflammatory and antioxidant effects.
A 2010 study on diabetic retinopathy studied the role of inflammation and potential CBD therapies for anti-inflammation treatment. In conclusion, they remarked that CBD caused certain activities like a self-defense system against inflammation and neurodegeneration.
2011 a busy CBD-inflammation research year
The therapeutic use of cannabidiol began to get attention in 2011. Consequently, a 2011 study concluded that cannabidiol is a promising prototype for anti-inflammatory drug development. Another 2011 lab study concluded that cannabidiol reduced intestinal inflammation through the control of neuroimmune axis.
Yet another 2011 study confirmed that Cannabidiol reduces Aβ-induced neuroinflammation. In addition, it showed that CBD promotes hippocampal neurogenesis through PPARγ involvement. The scientists concluded that these findings report the rather inescapable role of the PPARγ receptor in mediating CBD actions.
Cannabidiol, in a 2012 study, decreased inflammation in mice with acute lung injury. Another rodent test in 2012 concluded that cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors.
Mice with AP had positive anti-inflammatory effects due to CBD and O-1602. Also, cannabidiol improved the expression of GPR55 in the pancreatic tissue. A 2013 lab study also reconfirmed this.
In 2006 a clinical trial with 58 arthritis patients was done. Thereof, 31 were treated with a synthetic analog of cannabis. Synthetic analogs are, as you know, 100% chemically produced in pharmaceutical factories, opposite of being taken from plants.
Other scientists proved before that synthetic cannabinoids are less effective than organic cannabinoids. Nevertheless, the results showed significant improvements in pain due to inflammation reduction in the joints.
In addition in 2013, 21 Crohn’s disease patients that had failed to respond to the traditional steroid therapy participated in a clinical trial. Crohn’s disease is a chronic inflammatory condition of the GI tract. Finally, eleven patients were randomly selected for Crohn’s cannabis treatment, whilst the others received a placebo.
As a result, ten out of the eleven (91%) showed a clinical response with a rather significant reduction of their CDAI score (level of inflammation) of over 100. Furthermore, five out of eleven (45%) showed a complete remission after only a short eight-week treatment. Furthermore, they didn’t suffer from any side effects and reported improved appetite and sleep.
“As a result of CBD you have a global possibility of improvement in a number of inflammatory situations” according to Dr. Philip Blair, MD.
Lisa de Rose from the Netherlands suffered from arthroses (Osteoarthritis) and rheumatism. But she didn’t want to take the regular medication that the doctors prescribed her. Because she read the medicational instructions she understood the terrible side effects these meds would probably cause.
At the age of 82, she, therefore, started taking cannabis oil and CBD oil to mitigate pain caused by the inflammation in her joints. She didn’t use a large dosage but was pain-free for the last six years of her life. (see video below with English subtitles, “The story of Lisa de Roos -Because we all die”)
15-year-old Coltyn Turner has another remarkable story. He treated his chronic inflammatory disease of the GI tract (Crohn’s) with cannabis oil and completely got rid of it.
CBD Oil Dosage for Inflammation
Scientists proved in 2010 that THC and CBD acted synergistically to inhibit cell proliferation. This is just scientific proof of the effect of CBD because many of us already knew from our own anecdotal experiences: full-spectrum, whole plant, organic CBD oil is more effective.
Even small amounts of other cannabinoids and non-cannabinoid hemp components like terpenes boost each other’s effectiveness. This increases the overall CBD hemp benefits. The most important, dosage determining factor is the severity of the condition.
Although it is not possible to overdose cannabidiol, it is unnecessary to take too much if it is not needed. In case of inflammation, the severity spread might be even greater. Consequently, we recommend, when you have a mild inflammation, start with a smaller dose of 20 to 30 mg per day. Monitor the effects and double it after four days if it didn’t improve or if the improvements were weaker then expected.
With severe inflammatory diseases like Crohn’s disease, you can immediately start with 50 mg per day. Monitor and double in four days if needed. We have seen Crohn’s patients take several hundred milligrams per day along with cannabis oil to boost the healing effect even more.
No matter how you take the CBD oil, patients usually stay at the higher dosage for several weeks until the inflammation is improved. Then you can go back to a maintenance dosage of anywhere in the range of 25 to 50 mg per day. Just find out by testing what the minimum dosage is for avoiding inflammation return.
Please share your thoughts in the comment section below this article on what dosage worked best for your treatment. This way other people will benefit from your experience. Thanks!
Success Stories of Patients with Inflammation
We have carefully collected CBD testimonials for this particular condition to serve as proof and inspiration to others. Do not hesitate to record your own experience and share it with us so we can add it to this list and help thousands of patients more.
Overview of Scientific Studies and Reports
If you are interested in the medical proof and not scared of reading through some professional medical jargon, check out the studies below.