One of the many phytocannabinoids responsible for the medicinal benefits of cannabis; CBD is most commonly found in the hemp plant varieties. As legalization continues to thrive, CBD is also becoming more prevalent in medicinal cultivars such as ACDC and Charlottes Web. Cannabidiol (CBD) will often be combined with tetrahydrocannabinol (THC) medicine to alleviate the negative impairing effects and support additional advantages known as “the entourage effect”.
CBD for Effective Nausea Relief
Cannabidiol and its precursor acid form CBD-A (through decarboxylation, the acid will transform to CBD from heat over time). Both are powerful in managing acute and anticipatory nausea – which is often caused by memory triggers. Further studies provide evidence into CBD’s ability to regulate anxiety, a surprising factor in some nausea cases.
CBD is capable of interacting with multiple receptors and ion channels in the body. One, in particular, is the 5-hydroxytryptamine (5-HT) receptors where serotonin binds to the central and peripheral nervous system. In 2010, The British Journal of Pharmacology reviewed data from multiple animal studies and found CBD blocked the production of serotonin in the 5HT-1 receptor, which is thought to cause nausea. They were able to gather approximately ten additional species studies including shrews, pigeons, cats, and dogs.
By blocking the release of 5-HT (serotonin) neurons in the forebrain region, CBD has proved to decrease nausea when induced by medication. This analysis concludes that CBD is an excellent alternative for patients after recognizing the potentially dangerous side effects of pharmacological medications.